Big Ass Spider! is a 2013 science fiction comedy-horror film directed by Mike Mendez.
A giant alien spider escapes from a military lab and rampages the city of Los Angeles. When a massive military strike fails, it is up to a team of scientists and one clever exterminator to kill the creature before the city is destroyed.
Greg Grunberg as Alex Mathis
Clare Kramer as Lieutenant Karly Brant
Lombardo Boyar as Jose Ramos
Ray Wise as Major Braxton Tanner
Lin Shaye as Mrs. Jefferson
Patrick Bauchau as Lucas
Lloyd Kaufman as Himself
Alexis Kendra as Nurse Lisa (as Alexis Peters)
Adam Gierasch as Homeless Man
James C. Mathis as Street Cop